Quantum Inspired
Image Scanning Microspcopy
for biophyiscs

Quantum-Inspired Imaging with SPAD Array Detection

The Biophysics group is currently developing a quantum-inspired approach to Image Scanning Microscopy (ISM) by coupling a two-photon scanning microscope with a 7×7 SPAD (Single-Photon Avalanche Diode) array detector. This setup aims to enhance spatial resolution by a factor of 1.4 to 1.6 compared to conventional techniques.

In parallel, the group is working on a temporal acquisition strategy that explores correlations among different elements of the SPAD array, focusing on both blinking dynamics (microsecond scale) and antibunching signals (nanosecond scale) from single emitters. The goal is to exploit these temporal correlations to further improve spatial resolution and signal discrimination.